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Antibody drug separation using thermoresponsive anionic polymer brush modified beads with optimised electrostatic and hydrophobic interactions
Antibody drugs play an important role in biopharmaceuticals, because of the specificity for target biomolecules and reduction of side effects. Thus, separation and analysis techniques for these antibody drugs have increased in importance. In the present study, we develop functional chromatography ma...
Autores principales: | Nagase, Kenichi, Ishii, Saki, Ikeda, Koji, Yamada, Sota, Ichikawa, Daiju, Akimoto, Aya Mizutani, Hattori, Yutaka, Kanazawa, Hideko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385495/ https://www.ncbi.nlm.nih.gov/pubmed/32719404 http://dx.doi.org/10.1038/s41598-020-68707-7 |
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