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Androgen receptor co-regulation in prostate cancer

Prostate cancer (PCa) progression relies on androgen receptor (AR) action. Preventing AR's ligand-activation is the frontline treatment for metastatic PCa. Androgen deprivation therapy (ADT) that inhibits AR ligand-binding initially induces remission but eventually fails, mainly because of adap...

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Detalles Bibliográficos
Autores principales: Senapati, Dhirodatta, Kumari, Sangeeta, Heemers, Hannelore V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385509/
https://www.ncbi.nlm.nih.gov/pubmed/32742924
http://dx.doi.org/10.1016/j.ajur.2019.09.005