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Clonality analysis and IDH1 and IDH2 mutation detection in both components of dedifferentiated chondrosarcoma, implicated its monoclonal origin

Dedifferentiated chondrosarcoma (DDCS) is a highly malignant tumor that belongs to an uncommon subtype of chondrosarcoma with a poor prognosis. Microscopically, it is composed of highly differentiated chondrosarcoma and highly malignant noncartilaginous sarcomas with an abrupt interface. The questio...

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Detalles Bibliográficos
Autores principales: Yang, Tingting, Bai, Yueqing, Chen, Jie, Sun, Keyang, Luo, Yanli, Huang, Wentao, Zhang, Huizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385535/
https://www.ncbi.nlm.nih.gov/pubmed/32742915
http://dx.doi.org/10.1016/j.jbo.2020.100293