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In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19

Background: Human coronavirus (SARS-CoV-2) is causing a pandemic with significant morbidity and mortality. As no effective novel drugs are available currently, drug repurposing is an alternative intervention strategy. Here we present an  in silico drug repurposing study that implements successful co...

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Detalles Bibliográficos
Autores principales: BR, Bharath, Damle, Hrishikesh, Ganju, Shiban, Damle, Latha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385708/
https://www.ncbi.nlm.nih.gov/pubmed/32765844
http://dx.doi.org/10.12688/f1000research.24143.1