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Gemigliptin Inhibits Interleukin-1β–Induced Endothelial-Mesenchymal Transition via Canonical-Bone Morphogenetic Protein Pathway

BACKGROUND: Endothelial-to-mesenchymal transition (EndMT) contributes to inflammatory conditions inducing conversion of endothelial cells (ECs) into activated fibroblasts, promoting fibrotic diseases. Pro-inflammatory cytokine is the most potent inducer of EndMT. We investigated inhibition of interl...

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Detalles Bibliográficos
Autores principales: Hong, Oak-Kee, Lee, Seong-Su, Yoo, Soon Jib, Lee, Min-Kyung, Kim, Mee-Kyoung, Baek, Ki-Hyun, Song, Ki-Ho, Kwon, Hyuk-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386109/
https://www.ncbi.nlm.nih.gov/pubmed/32615723
http://dx.doi.org/10.3803/EnM.2020.35.2.384