Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

BACKGROUND: SARS-CoV-2 is a recently emerged respiratory pathogen that has significantly impacted global human health. We wanted to rapidly characterise the transcriptomic, proteomic and phosphoproteomic landscape of this novel coronavirus to provide a fundamental description of the virus’s genomic...

Descripción completa

Detalles Bibliográficos
Autores principales: Davidson, Andrew D., Williamson, Maia Kavanagh, Lewis, Sebastian, Shoemark, Deborah, Carroll, Miles W., Heesom, Kate J., Zambon, Maria, Ellis, Joanna, Lewis, Philip A., Hiscox, Julian A., Matthews, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386171/
https://www.ncbi.nlm.nih.gov/pubmed/32723359
http://dx.doi.org/10.1186/s13073-020-00763-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386171/
https://www.ncbi.nlm.nih.gov/pubmed/32723359
http://dx.doi.org/10.1186/s13073-020-00763-0

Ejemplares similares