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Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein
BACKGROUND: SARS-CoV-2 is a recently emerged respiratory pathogen that has significantly impacted global human health. We wanted to rapidly characterise the transcriptomic, proteomic and phosphoproteomic landscape of this novel coronavirus to provide a fundamental description of the virus’s genomic...
Autores principales: | Davidson, Andrew D., Williamson, Maia Kavanagh, Lewis, Sebastian, Shoemark, Deborah, Carroll, Miles W., Heesom, Kate J., Zambon, Maria, Ellis, Joanna, Lewis, Philip A., Hiscox, Julian A., Matthews, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386171/ https://www.ncbi.nlm.nih.gov/pubmed/32723359 http://dx.doi.org/10.1186/s13073-020-00763-0 |
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