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instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder
Hi-C exploits contact frequencies between pairs of loci to bridge and order contigs during genome assembly, resulting in chromosome-level assemblies. Because few robust programs are available for this type of data, we developed instaGRAAL, a complete overhaul of the GRAAL program, which has adapted...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386250/ https://www.ncbi.nlm.nih.gov/pubmed/32552806 http://dx.doi.org/10.1186/s13059-020-02041-z |