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Cancer-Associated Mutations in Normal Colorectal Mucosa Adjacent to Sporadic Neoplasia

INTRODUCTION: Colorectal cancer arises in a multistep process of carcinogenesis from normal mucosa. The earliest precursor might be a morphologically inconspicuous precancerous field, harboring cancer-associated mutations. METHODS: We systematically analyzed genetic alterations in 77 tissue samples...

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Detalles Bibliográficos
Autores principales: Zhan, Tianzuo, Belle, Sebastian, Valentini, Erica, Herrmann, Simon, Miersch, Thilo, Li, Moying, Gaiser, Timo, Boutros, Michael, Ebert, Matthias P., Betge, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386331/
https://www.ncbi.nlm.nih.gov/pubmed/32764203
http://dx.doi.org/10.14309/ctg.0000000000000212