Inhibitors of VPS34 and lipid metabolism suppress SARS-CoV-2 replication

Therapeutics targeting replication of SARS coronavirus 2 (SARS-CoV-2) are urgently needed. Coronaviruses rely on host membranes for entry, establishment of replication centers and egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways have previously shown promise as a...

Descripción completa

Detalles Bibliográficos
Autores principales: Silvas, Jesus A., Jureka, Alexander S., Nicolini, Anthony M., Chvatal, Stacie A., Basler, Christopher F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386504/
https://www.ncbi.nlm.nih.gov/pubmed/32743584
http://dx.doi.org/10.1101/2020.07.18.210211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386504/
https://www.ncbi.nlm.nih.gov/pubmed/32743584
http://dx.doi.org/10.1101/2020.07.18.210211

Ejemplares similares