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Pterostilbene protects cochlea from ototoxicity in streptozotocin-induced diabetic rats by inhibiting apoptosis

Diabetes mellitus (DM) causes ototoxicity by inducing oxidative stress, microangiopathy, and apoptosis in the cochlear sensory hair cells. The natural anti-oxidant pterostilbene (PTS) (trans-3,5-dimethoxy-4-hydroxystylbene) has been reported to relieve oxidative stress and apoptosis in DM, but its r...

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Detalles Bibliográficos
Autores principales: Özdaş, Sibel, Taştekin, Bora, Gürgen, Seren G., Özdaş, Talih, Pelit, Aykut, Erkan, Sanem O., Tuhanioğlu, Birgül, Gülnar, Birgül, Görgülü, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386625/
https://www.ncbi.nlm.nih.gov/pubmed/32722679
http://dx.doi.org/10.1371/journal.pone.0228429