Heterogeneous, delayed-onset killing by multiple-hitting T cells: Stochastic simulations to assess methods for analysis of imaging data

Although quantitative insights into the killing behaviour of Cytotoxic T Lymphocytes (CTLs) are necessary for the rational design of immune-based therapies, CTL killing function remains insufficiently characterised. One established model of CTL killing treats CTL cytotoxicity as a Poisson process, b...

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Detalles Bibliográficos
Autores principales: Beck, Richard J., Bijker, Dario I., Beltman, Joost B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386628/
https://www.ncbi.nlm.nih.gov/pubmed/32658891
http://dx.doi.org/10.1371/journal.pcbi.1007972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386628/
https://www.ncbi.nlm.nih.gov/pubmed/32658891
http://dx.doi.org/10.1371/journal.pcbi.1007972

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