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Serotonin-evoked cytosolic Ca(2+) release and opioid receptor expression are upregulated in articular cartilage chondrocytes from osteoarthritic joints in horses

Osteoarthritis is a pain-associated progressive disease and pain mediators, such as opioid receptors, expressed in articular cartilage could represent novel therapeutic targets. Acute and chronic stages of OA indicate different metabolic abilities of the chondrocytes depending on inflammatory state....

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Detalles Bibliográficos
Autores principales: Skiöldebrand, Eva, Ley, Cecilia, Björklund, Ulrika, Lindahl, Anders, Hansson, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386637/
https://www.ncbi.nlm.nih.gov/pubmed/32734095
http://dx.doi.org/10.1016/j.vas.2019.100078