Comparison of two reducing agents dithiothreitol and tris(3-hydroxypropyl)phosphine for in vitro kinetic assay of vitamin K epoxide reductase

Vitamin K epoxide reductase (VKOR) is a target enzyme for anticoagulants, such as warfarin, that are used as medicines or rodenticides. Assessing VKOR activity is required to ensure the proper usage of these drugs. Dithiothreitol (DTT) is a typical disulfide reductant that is used as a substrate for...

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Detalles Bibliográficos
Autores principales: Takeda, Kazuki, Morita, Ayuko, Ikenaka, Yoshinori, Nakayama, Shouta M.M., Ishizuka, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386777/
https://www.ncbi.nlm.nih.gov/pubmed/32734105
http://dx.doi.org/10.1016/j.vas.2020.100095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386777/
https://www.ncbi.nlm.nih.gov/pubmed/32734105
http://dx.doi.org/10.1016/j.vas.2020.100095

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