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No relation between docetaxel administration route and high‐grade diarrhea incidence

Oral administration of docetaxel in combination with the CYP3A4 inhibitor ritonavir is used in clinical trials to improve oral bioavailability of docetaxel. Diarrhea was the most commonly observed and dose‐limiting toxicity. This study combined preclinical and clinical data and investigated incidenc...

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Detalles Bibliográficos
Autores principales: Hendrikx, Jeroen J. M. A., Stuurman, Frederik E., Song, Ji‐Ying, de Weger, Vincent A., Lagas, Jurjen S., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H., Schellens, Jan H. M., Marchetti, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387127/
https://www.ncbi.nlm.nih.gov/pubmed/32725720
http://dx.doi.org/10.1002/prp2.633