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Orientation of immobilized antigens on common surfaces by a simple computational model: Exposition of SARS-CoV-2 Spike protein RBD epitopes

The possibility of immobilizing a protein with antigenic properties on a solid support offers significant possibilities in the development of immunosensors and vaccine formulations. For both applications, the orientation of the antigen should ensure ready accessibility of the antibodies to the epito...

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Detalles Bibliográficos
Autores principales: Cerofolini, Linda, Fragai, Marco, Luchinat, Claudio, Ravera, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387289/
https://www.ncbi.nlm.nih.gov/pubmed/32745829
http://dx.doi.org/10.1016/j.bpc.2020.106441