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Orientation of immobilized antigens on common surfaces by a simple computational model: Exposition of SARS-CoV-2 Spike protein RBD epitopes
The possibility of immobilizing a protein with antigenic properties on a solid support offers significant possibilities in the development of immunosensors and vaccine formulations. For both applications, the orientation of the antigen should ensure ready accessibility of the antibodies to the epito...
Autores principales: | Cerofolini, Linda, Fragai, Marco, Luchinat, Claudio, Ravera, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387289/ https://www.ncbi.nlm.nih.gov/pubmed/32745829 http://dx.doi.org/10.1016/j.bpc.2020.106441 |
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