Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders

Clonal hematopoiesis is frequently observed in elderly people. To investigate the prevalence and dynamics of genetic alterations among healthy elderly individuals, a cohort of 50 people >80 years was genotyped for commonly mutated leukemia-associated genes by targeted deep next-generation sequenc...

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Detalles Bibliográficos
Autores principales: Midic, Danica, Rinke, Jenny, Perner, Florian, Müller, Violetta, Hinze, Anna, Pester, Frank, Landschulze, Jürgen, Ernst, Jana, Gruhn, Bernd, Matziolis, Georg, Heidel, Florian H., Hochhaus, Andreas, Ernst, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387320/
https://www.ncbi.nlm.nih.gov/pubmed/32457355
http://dx.doi.org/10.1038/s41375-020-0869-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387320/
https://www.ncbi.nlm.nih.gov/pubmed/32457355
http://dx.doi.org/10.1038/s41375-020-0869-y

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