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Prevalence and dynamics of clonal hematopoiesis caused by leukemia-associated mutations in elderly individuals without hematologic disorders
Clonal hematopoiesis is frequently observed in elderly people. To investigate the prevalence and dynamics of genetic alterations among healthy elderly individuals, a cohort of 50 people >80 years was genotyped for commonly mutated leukemia-associated genes by targeted deep next-generation sequenc...
Autores principales: | Midic, Danica, Rinke, Jenny, Perner, Florian, Müller, Violetta, Hinze, Anna, Pester, Frank, Landschulze, Jürgen, Ernst, Jana, Gruhn, Bernd, Matziolis, Georg, Heidel, Florian H., Hochhaus, Andreas, Ernst, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387320/ https://www.ncbi.nlm.nih.gov/pubmed/32457355 http://dx.doi.org/10.1038/s41375-020-0869-y |
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