Safety of Janus Kinase Inhibitors in Older Patients: A Focus on the Thromboembolic Risk

The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) pathway is a membrane-to-nucleus signaling cascade that effects activation of gene transcription. JAK inhibitors have demonstrated effectiveness in autoimmune diseases such as rheumatoid arthritis. An increased risk of in...

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Detalles Bibliográficos
Autores principales: Rajasimhan, Suraj, Pamuk, Omer, Katz, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Current Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387323/
https://www.ncbi.nlm.nih.gov/pubmed/32514874
http://dx.doi.org/10.1007/s40266-020-00775-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387323/
https://www.ncbi.nlm.nih.gov/pubmed/32514874
http://dx.doi.org/10.1007/s40266-020-00775-w

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