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Simultaneous analysis of multiple oligonucleotides by temperature-responsive chromatography using a poly(N-isopropylacrylamide)-based stationary phase

Oligonucleotide therapeutics have contributed remarkably to healthcare, being well suited for the treatment of intractable diseases that are difficult to approach using conventional drug modalities. However, as common techniques of oligonucleotide analysis rely on reversed-phase or ion-exchange liqu...

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Detalles Bibliográficos
Autores principales: Maekawa, Yutaro, Yamazaki, Kaichi, Ihara, Miwa, Nagase, Kenichi, Kanazawa, Hideko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387324/
https://www.ncbi.nlm.nih.gov/pubmed/32529301
http://dx.doi.org/10.1007/s00216-020-02749-8