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Simultaneous analysis of multiple oligonucleotides by temperature-responsive chromatography using a poly(N-isopropylacrylamide)-based stationary phase
Oligonucleotide therapeutics have contributed remarkably to healthcare, being well suited for the treatment of intractable diseases that are difficult to approach using conventional drug modalities. However, as common techniques of oligonucleotide analysis rely on reversed-phase or ion-exchange liqu...
Autores principales: | Maekawa, Yutaro, Yamazaki, Kaichi, Ihara, Miwa, Nagase, Kenichi, Kanazawa, Hideko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387324/ https://www.ncbi.nlm.nih.gov/pubmed/32529301 http://dx.doi.org/10.1007/s00216-020-02749-8 |
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