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Cholesterol modulates presynaptic and postsynaptic properties of excitatory synaptic transmission

Cholesterol is a structural component of cellular membranes particularly enriched in synapses but its role in synaptic transmission remains poorly understood. We used rat hippocampal cultures and their acute cholesterol depletion by methyl-β-cyclodextrin as a tool to describe the physiological role...

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Detalles Bibliográficos
Autores principales: Korinek, Miloslav, Gonzalez-Gonzalez, Inmaculada M., Smejkalova, Tereza, Hajdukovic, Dragana, Skrenkova, Kristyna, Krusek, Jan, Horak, Martin, Vyklicky, Ladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387334/
https://www.ncbi.nlm.nih.gov/pubmed/32724221
http://dx.doi.org/10.1038/s41598-020-69454-5