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Cholesterol modulates presynaptic and postsynaptic properties of excitatory synaptic transmission
Cholesterol is a structural component of cellular membranes particularly enriched in synapses but its role in synaptic transmission remains poorly understood. We used rat hippocampal cultures and their acute cholesterol depletion by methyl-β-cyclodextrin as a tool to describe the physiological role...
Autores principales: | Korinek, Miloslav, Gonzalez-Gonzalez, Inmaculada M., Smejkalova, Tereza, Hajdukovic, Dragana, Skrenkova, Kristyna, Krusek, Jan, Horak, Martin, Vyklicky, Ladislav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387334/ https://www.ncbi.nlm.nih.gov/pubmed/32724221 http://dx.doi.org/10.1038/s41598-020-69454-5 |
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