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Diethylcarbamazine activates TRP channels including TRP-2 in filaria, Brugia malayi

Diethylcarbamazine is an important classic drug used for prevention and treatment of lymphatic filariasis and loiasis, diseases caused by filarial nematodes. Despite many studies, its site of action has not been established. Until now, the consensus has been that diethylcarbamazine works by activati...

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Detalles Bibliográficos
Autores principales: Verma, Saurabh, Kashyap, Sudhanva S., Robertson, Alan P., Martin, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387335/
https://www.ncbi.nlm.nih.gov/pubmed/32724078
http://dx.doi.org/10.1038/s42003-020-01128-4