α-Hemolysin of uropathogenic E. coli regulates NLRP3 inflammasome activation and mitochondrial dysfunction in THP-1 macrophages

Hemolysin expressing UPEC strains have been associated with severe advanced kidney pathologies, such as cystitis and pyelonephritis, which are associated with an inflammatory response. Macrophages play an important role in regulating an inflammatory response during a urinary tract infection. We have...

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Detalles Bibliográficos
Autores principales: Verma, Vivek, Kumar, Parveen, Gupta, Surbhi, Yadav, Sonal, Dhanda, Rakesh Singh, Thorlacius, Henrik, Yadav, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387347/
https://www.ncbi.nlm.nih.gov/pubmed/32724079
http://dx.doi.org/10.1038/s41598-020-69501-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387347/
https://www.ncbi.nlm.nih.gov/pubmed/32724079
http://dx.doi.org/10.1038/s41598-020-69501-1

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