Cigarette smoke induces endoplasmic reticulum stress and suppresses efferocytosis through the activation of RhoA

Impaired efferocytosis is a key mechanism of inflammatory lung diseases, including chronic obstructive pulmonary disease and cystic fibrosis. Cigarette smoking activates RhoA and impairs efferocytosis in alveolar macrophages, but the mechanism has not been fully elucidated. We investigated the role...

Descripción completa

Detalles Bibliográficos
Autores principales: Ito, Hiroyuki, Yamashita, Yoshiro, Tanaka, Takeshi, Takaki, Masahiro, Le, Minh Nhat, Yoshida, Lay-Myint, Morimoto, Konosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387437/
https://www.ncbi.nlm.nih.gov/pubmed/32724133
http://dx.doi.org/10.1038/s41598-020-69610-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387437/
https://www.ncbi.nlm.nih.gov/pubmed/32724133
http://dx.doi.org/10.1038/s41598-020-69610-x

Ejemplares similares