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Cigarette smoke induces endoplasmic reticulum stress and suppresses efferocytosis through the activation of RhoA
Impaired efferocytosis is a key mechanism of inflammatory lung diseases, including chronic obstructive pulmonary disease and cystic fibrosis. Cigarette smoking activates RhoA and impairs efferocytosis in alveolar macrophages, but the mechanism has not been fully elucidated. We investigated the role...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387437/ https://www.ncbi.nlm.nih.gov/pubmed/32724133 http://dx.doi.org/10.1038/s41598-020-69610-x |