In vitro and ex vivo gene expression profiling reveals differential kinetic response of HSPs and UPR genes is associated with PI resistance in multiple myeloma

Extensive inter-individual variation in response to chemotherapy (sensitive vs resistant tumors) is a serious cause of concern in the treatment of multiple myeloma (MM). In this study, we used human myeloma cell lines (HMCLs), and patient-derived CD138+ cells to compare kinetic changes in gene expre...

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Detalles Bibliográficos
Autores principales: Mitra, Amit Kumar, Kumar, Harish, Ramakrishnan, Vijay, Chen, Li, Baughn, Linda, Kumar, Shaji, Rajkumar, S. Vincent, Van Ness, Brian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387444/
https://www.ncbi.nlm.nih.gov/pubmed/32724061
http://dx.doi.org/10.1038/s41408-020-00344-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387444/
https://www.ncbi.nlm.nih.gov/pubmed/32724061
http://dx.doi.org/10.1038/s41408-020-00344-9

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