Genome-wide association study and polygenic risk score analysis of esketamine treatment response

To elucidate the genetic underpinnings of the antidepressant efficacy of S-ketamine (esketamine) nasal spray in major depressive disorder (MDD), we performed a genome-wide association study (GWAS) in cohorts of European ancestry (n = 527). This analysis was followed by a polygenic risk score approac...

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Detalles Bibliográficos
Autores principales: Li, Qingqin S., Wajs, Ewa, Ochs-Ross, Rachel, Singh, Jaskaran, Drevets, Wayne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387452/
https://www.ncbi.nlm.nih.gov/pubmed/32724131
http://dx.doi.org/10.1038/s41598-020-69291-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387452/
https://www.ncbi.nlm.nih.gov/pubmed/32724131
http://dx.doi.org/10.1038/s41598-020-69291-6

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