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β1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells

Tendons are specialized tissues composed primarily of load-responsive fibroblasts (tenocytes) embedded in a collagen-rich extracellular matrix. Habitual mechanical loading or targeted exercise causes tendon cells to increase the stiffness of the extracellular matrix; this adaptation may occur in par...

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Detalles Bibliográficos
Autores principales: Mousavizadeh, Rouhollah, Hojabrpour, Payman, Eltit, Felipe, McDonald, Paul C., Dedhar, Shoukat, McCormack, Robert G., Duronio, Vincent, Jafarnejad, Seyed Mehdi, Scott, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387456/
https://www.ncbi.nlm.nih.gov/pubmed/32724089
http://dx.doi.org/10.1038/s41598-020-69267-6