Cancer-associated fibroblasts stimulate primary tumor growth and metastatic spread in an orthotopic prostate cancer xenograft model

The unique microenvironment of the prostate plays a crucial role in the development and progression of prostate cancer (PCa). We examined the effects of cancer-associated fibroblasts (CAFs) on PCa progression using patient-derived fibroblast primary cultures in a representative orthotopic xenograft...

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Detalles Bibliográficos
Autores principales: Linxweiler, Johannes, Hajili, Turkan, Körbel, Christina, Berchem, Carolina, Zeuschner, Philip, Müller, Andreas, Stöckle, Michael, Menger, Michael D., Junker, Kerstin, Saar, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387494/
https://www.ncbi.nlm.nih.gov/pubmed/32724081
http://dx.doi.org/10.1038/s41598-020-69424-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387494/
https://www.ncbi.nlm.nih.gov/pubmed/32724081
http://dx.doi.org/10.1038/s41598-020-69424-x

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