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Ubiquitin–proteasome system, lipid metabolism and DNA damage repair are triggered by antipsychotic medication in human oligodendrocytes: implications in schizophrenia

Schizophrenia is a chronic, severe and disabling psychiatric disorder, whose treatment is based on psychosocial interventions and the use of antipsychotic drugs. While the effects of these drugs are well elucidated in neuronal cells, they are still not so clear in oligodendrocytes, which play a vita...

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Detalles Bibliográficos
Autores principales: Seabra, Gabriela, de Almeida, Valéria, Reis-de-Oliveira, Guilherme, Crunfli, Fernanda, Antunes, André Saraiva Leão Marcelo, Martins-de-Souza, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387551/
https://www.ncbi.nlm.nih.gov/pubmed/32724114
http://dx.doi.org/10.1038/s41598-020-69543-5