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Ubiquitin–proteasome system, lipid metabolism and DNA damage repair are triggered by antipsychotic medication in human oligodendrocytes: implications in schizophrenia
Schizophrenia is a chronic, severe and disabling psychiatric disorder, whose treatment is based on psychosocial interventions and the use of antipsychotic drugs. While the effects of these drugs are well elucidated in neuronal cells, they are still not so clear in oligodendrocytes, which play a vita...
Autores principales: | Seabra, Gabriela, de Almeida, Valéria, Reis-de-Oliveira, Guilherme, Crunfli, Fernanda, Antunes, André Saraiva Leão Marcelo, Martins-de-Souza, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387551/ https://www.ncbi.nlm.nih.gov/pubmed/32724114 http://dx.doi.org/10.1038/s41598-020-69543-5 |
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