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Decrease of laminin-511 in the basement membrane due to photoaging reduces epidermal stem/progenitor cells

Daily sunlight exposure damages the epidermal basement membrane (BM) and disrupts epidermal homeostasis. Inter-follicular epidermal stem cells (IFE-SCs) regulate epidermal proliferation and differentiation, which supports epidermal homeostasis. Here, we examine how photoaging affects the function of...

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Detalles Bibliográficos
Autores principales: Iriyama, Shunsuke, Yasuda, Masahito, Nishikawa, Saori, Takai, Eisuke, Hosoi, Junichi, Amano, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387558/
https://www.ncbi.nlm.nih.gov/pubmed/32724130
http://dx.doi.org/10.1038/s41598-020-69558-y