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T-bet Expression in Peripheral Th17.0 Cells Is Associated With Pulmonary Function Changes in Sarcoidosis

Background: Interferon-gamma (IFN-γ) is a key mediator of sarcoidosis-related granulomatous inflammation. Previous findings of IFN-γ-producing Th17 cells in bronchoalveolar lavage fluid from sarcoidosis patients invokes the transition of Th17.0 cells to Th17.1 cells in the disease's pathogenesi...

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Detalles Bibliográficos
Autores principales: Arger, Nicholas K., Machiraju, Siddharth, Allen, Isabel E., Woodruff, Prescott G., Koth, Laura L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387715/
https://www.ncbi.nlm.nih.gov/pubmed/32774332
http://dx.doi.org/10.3389/fimmu.2020.01129