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Nearest-Neighbor Projected Distance Regression for Epistasis Detection in GWAS With Population Structure Correction

Nearest-neighbor Projected-Distance Regression (NPDR) is a feature selection technique that uses nearest-neighbors in high dimensional data to detect complex multivariate effects including epistasis. NPDR uses a regression formalism that allows statistical significance testing and efficient control...

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Detalles Bibliográficos
Autores principales: Arabnejad, Marziyeh, Montgomery, Courtney G., Gaffney, Patrick M., McKinney, Brett A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387719/
https://www.ncbi.nlm.nih.gov/pubmed/32774345
http://dx.doi.org/10.3389/fgene.2020.00784