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A MARTX Toxin rtxA Gene Is Controlled by Host Environmental Signals through a CRP-Coordinated Regulatory Network in Vibrio vulnificus

A multifunctional autoprocessing repeats-in-toxin (MARTX) toxin plays an essential role in the virulence of many pathogens, including a fulminating human pathogen Vibrio vulnificus. H-NS and HlyU repress and derepress expression of the MARTX toxin gene rtxA in V. vulnificus, respectively. However, l...

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Detalles Bibliográficos
Autores principales: Lee, Zee-Won, Hwang, Seung-Ho, Choi, Garam, Jang, Kyung Ku, Lee, Tae Hee, Chung, Kyung Min, Kim, Byoung Sik, Choi, Sang Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387792/
https://www.ncbi.nlm.nih.gov/pubmed/32723914
http://dx.doi.org/10.1128/mBio.00723-20