A Cytoplasmic Heme Sensor Illuminates the Impacts of Mitochondrial and Vacuolar Functions and Oxidative Stress on Heme-Iron Homeostasis in Cryptococcus neoformans

Pathogens must compete with hosts to acquire sufficient iron for proliferation during pathogenesis. The pathogenic fungus Cryptococcus neoformans is capable of acquiring iron from heme, the most abundant source in vertebrate hosts, although the mechanisms of heme sensing and acquisition are not enti...

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Detalles Bibliográficos
Autores principales: Bairwa, Gaurav, Sánchez-León, Eddy, Do, Eunsoo, Jung, Won Hee, Kronstad, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387795/
https://www.ncbi.nlm.nih.gov/pubmed/32723917
http://dx.doi.org/10.1128/mBio.00986-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387795/
https://www.ncbi.nlm.nih.gov/pubmed/32723917
http://dx.doi.org/10.1128/mBio.00986-20

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