Interactions of Monocytes, HIV, and ART Identified by an Innovative scRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities

HIV reservoirs persist despite successful antiretroviral therapy (ART) and are a major obstacle to the eradication and cure of HIV. The mature monocyte subset, CD14(+)CD16(+), contributes to viral reservoirs and HIV-associated comorbidities. Only a subset of monocytes harbors HIV (HIV(+)), while the...

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Detalles Bibliográficos
Autores principales: León-Rivera, Rosiris, Morsey, Brenda, Niu, Meng, Fox, Howard S., Berman, Joan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387797/
https://www.ncbi.nlm.nih.gov/pubmed/32723919
http://dx.doi.org/10.1128/mBio.01037-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387797/
https://www.ncbi.nlm.nih.gov/pubmed/32723919
http://dx.doi.org/10.1128/mBio.01037-20

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