FEDS: a Novel Fluorescence-Based High-Throughput Method for Measuring DNA Supercoiling In Vivo

DNA supercoiling (DS) is essential for life because it controls critical processes, including transcription, replication, and recombination. Current methods to measure DNA supercoiling in vivo are laborious and unable to examine single cells. Here, we report a method for high-throughput measurement...

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Detalles Bibliográficos
Autores principales: Duprey, Alexandre, Groisman, Eduardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387798/
https://www.ncbi.nlm.nih.gov/pubmed/32723920
http://dx.doi.org/10.1128/mBio.01053-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387798/
https://www.ncbi.nlm.nih.gov/pubmed/32723920
http://dx.doi.org/10.1128/mBio.01053-20

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