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Inhibition of complex I-III activity of brain mitochondria after intracerebroventricular administration of streptozotocin in rats is possibly related to loss of body weight

The effects of streptozotocin (STZ) on the brain after intracerebroventricular (ICV) administration in rodents have been suggested to mimic the pathogenesis of sporadic Alzheimer's disease (AD). Oxidative damage, decreased glucose utilization, mitochondrial bioenergetic changes, neuroinflammati...

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Detalles Bibliográficos
Autores principales: Poddar, Jit, Singh, Sukhpal, Kumar, Pardeep, Bali, Sharadendu, Gupta, Sumeet, Chakrabarti, Sasanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387826/
https://www.ncbi.nlm.nih.gov/pubmed/32743098
http://dx.doi.org/10.1016/j.heliyon.2020.e04490