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Inhibition of complex I-III activity of brain mitochondria after intracerebroventricular administration of streptozotocin in rats is possibly related to loss of body weight
The effects of streptozotocin (STZ) on the brain after intracerebroventricular (ICV) administration in rodents have been suggested to mimic the pathogenesis of sporadic Alzheimer's disease (AD). Oxidative damage, decreased glucose utilization, mitochondrial bioenergetic changes, neuroinflammati...
Autores principales: | Poddar, Jit, Singh, Sukhpal, Kumar, Pardeep, Bali, Sharadendu, Gupta, Sumeet, Chakrabarti, Sasanka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387826/ https://www.ncbi.nlm.nih.gov/pubmed/32743098 http://dx.doi.org/10.1016/j.heliyon.2020.e04490 |
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