The first study in pediatric: Population pharmacokinetics of sirolimus and its application in Chinese children with immune cytopenia

The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. T...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaoling, Zhao, Yiming, Gu, Hao, Zhao, Libo, Zang, Yannan, Wang, Xiaoling, Wu, Runhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388097/
https://www.ncbi.nlm.nih.gov/pubmed/32720540
http://dx.doi.org/10.1177/2058738420934936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388097/
https://www.ncbi.nlm.nih.gov/pubmed/32720540
http://dx.doi.org/10.1177/2058738420934936

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