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The first study in pediatric: Population pharmacokinetics of sirolimus and its application in Chinese children with immune cytopenia
The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. T...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388097/ https://www.ncbi.nlm.nih.gov/pubmed/32720540 http://dx.doi.org/10.1177/2058738420934936 |