Homocysteine induces mitochondrial dysfunction and oxidative stress in myocardial ischemia/reperfusion injury through stimulating ROS production and the ERK1/2 signaling pathway

Acute oxidative stress and mitochondrial dysfunction are crucial for acute myocardial ischemia-reperfusion (AMI/R) injury, which may induce cell or mitochondrial membrane rupture and myocardial infarction. Plasma homocysteine (Hcy) expression levels are positively associated with risk of cardiovascu...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Niu, Heping, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388298/
https://www.ncbi.nlm.nih.gov/pubmed/32742337
http://dx.doi.org/10.3892/etm.2020.8735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388298/
https://www.ncbi.nlm.nih.gov/pubmed/32742337
http://dx.doi.org/10.3892/etm.2020.8735

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