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SIRT3 is a downstream target of PPAR-α implicated in high glucose-induced cardiomyocyte injury in AC16 cells

Diabetic cardiomyopathy (DCM) is a worldwide public health concern that continues to display rapid growth trends. This study investigated the function of sirtuin 3 (SIRT3), a primary mitochondrial deacetylase with important roles in antioxidant defense and oxidative metabolism, during high glucose-i...

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Detalles Bibliográficos
Autores principales: Zong, Xiaojuan, Cheng, Kuan, Yin, Guizhi, Wu, Zhaodi, Su, Qian, Yu, Dong, Liao, Pengfei, Hu, Wei, Chen, Yueguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388318/
https://www.ncbi.nlm.nih.gov/pubmed/32742361
http://dx.doi.org/10.3892/etm.2020.8860