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CCR3-shRNA promotes apoptosis and inhibits chemotaxis and degranulation of mouse mast cells

Mast cells (MCs) are the major effector cells of allergic rhinitis (AR). The present study aimed to investigate the effects of C-C chemokine receptor type 3 (CCR3) on the proliferation, apoptosis, chemotaxis and activated degranulation of mouse MCs. Mouse bone marrow-derived MCs were cultured in vit...

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Detalles Bibliográficos
Autores principales: Peng, Haisen, Liao, Bing, Zhu, Xinhua, Liu, Yuehui, Jiang, Yinli, Wu, Shuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388334/
https://www.ncbi.nlm.nih.gov/pubmed/32742345
http://dx.doi.org/10.3892/etm.2020.8737