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The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is more common and severe in women compared to men. Both women and men with RA express autoantibodies to post-translationally modified antigens, including citrullinated and homocitrullinated proteins or peptides. These autoantibodies are strongly linked with the HLA-DR4 gen...

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Detalles Bibliográficos
Autores principales: Cairns, Ewa, Saunders, Sheri, Bell, David A., Blackler, Garth, Lac, Patrick, Barra, Lillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388343/
https://www.ncbi.nlm.nih.gov/pubmed/32743533
http://dx.doi.org/10.1016/j.jtauto.2020.100053