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No evidence of autoimmunity to human OX(1) or OX(2) orexin receptors in Pandemrix-vaccinated narcoleptic children

Narcolepsy type 1, likely an immune-mediated disease, is characterized by excessive daytime sleepiness and cataplexy. The disease is strongly associated with human leukocyte antigen (HLA) DQB1∗06:02. A significant increase in the incidence of childhood and adolescent narcolepsy was observed after a...

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Detalles Bibliográficos
Autores principales: Melén, Krister, Jalkanen, Pinja, Kukkonen, Jyrki P., Partinen, Markku, Nohynek, Hanna, Vuorela, Arja, Vaarala, Outi, Freitag, Tobias L., Meri, Seppo, Julkunen, Ilkka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388359/
https://www.ncbi.nlm.nih.gov/pubmed/32743535
http://dx.doi.org/10.1016/j.jtauto.2020.100055